BDBM50291798 1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL267692
SMILES CC(C)(C)c1cccc(c1)N1C(N)=NC(N)=NC1(C)C
InChI Key InChIKey=HRDHEUBWDVJRHA-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50291798
Affinity DataKi: 3.20nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 178nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 214nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Leishmania major)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 5.75E+3nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.91E+4nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 1.91E+4nMAssay Description:Inhibition constant against binding of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.02E+4nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair