BDBM50291798 1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL267692

SMILES CC(C)(C)c1cccc(c1)N1C(N)=NC(N)=NC1(C)C

InChI Key InChIKey=HRDHEUBWDVJRHA-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50291798   

TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50291798(1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  3.20nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50291798(1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  178nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291798(1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  214nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50291798(1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  5.75E+3nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291798(1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  1.91E+4nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Uniroyal Chemical

Curated by ChEMBL
LigandPNGBDBM50291798(1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  1.91E+4nMAssay Description:Inhibition constant against binding of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50291798(1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  3.02E+4nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed