BDBM50293064 7-({[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL523107::Immucillins, 10
SMILES OCC(CO)(CO)NCc1c[nH]c2c1nc[nH]c2=O
InChI Key InChIKey=UJESFEKRDYMZED-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50293064
Affinity DataKi: 0.620nMAssay Description:Inhibition of human PNP by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.620nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
Affinity DataKd: 163nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 2 hits for monomerid = 50293064
ITC DataΔG°: -12.6kcal/mole logk: 1.78E+9
pH: 7.4 T: 25.00°C
pH: 7.4 T: 25.00°C
ITC DataΔH°: -13.3kcal/mole
pH: 7.4 T: 27.00°C
pH: 7.4 T: 27.00°C