BDBM50293161 1-(dimethylamino)-3-(4-(4-(6-morpholinopyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)phenoxy)propan-2-ol::CHEMBL521871

SMILES CN(C)CC(O)COc1ccc(Nc2nccc(n2)-c2cnn3nc(ccc23)N2CCOCC2)cc1

InChI Key InChIKey=GBRORGYPYNNDGL-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293161   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293161(1-(dimethylamino)-3-(4-(4-(6-morpholinopyrazolo[1,...)
Affinity DataIC50:  38nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293161(1-(dimethylamino)-3-(4-(4-(6-morpholinopyrazolo[1,...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293161(1-(dimethylamino)-3-(4-(4-(6-morpholinopyrazolo[1,...)
Affinity DataIC50:  690nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed