BDBM50293412 6-[5-(Adamant-1-yl)-4-[(2-methoxyethoxy)methoxy]-2-methylphenyl]-5-chloro-2-naphthoic acid::CHEMBL563805

SMILES COCCOCOc1cc(C)c(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1Cl)C(O)=O

InChI Key InChIKey=GTQRCNNQKSSSCI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293412   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Universidade De Vigo

Curated by ChEMBL
LigandPNGBDBM50293412(6-[5-(Adamant-1-yl)-4-[(2-methoxyethoxy)methoxy]-2...)
Affinity DataIC50:  7.06E+3nMAssay Description:Inhibition of recombinant IKKbeta (unknown origin) using ulight-IkappaomegaBalpha as substrate after 2 hrs by LANCE ultra TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Mus musculus)
Universidade De Vigo

Curated by ChEMBL
LigandPNGBDBM50293412(6-[5-(Adamant-1-yl)-4-[(2-methoxyethoxy)methoxy]-2...)
Affinity DataEC50:  667nMAssay Description:Transactivation of Gal4-LBD fused mouse RXRalpha (218 to 467) transfected in african green monkey CV1 cells assessed as luciferase activity at after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed