BDBM50293659 CHEMBL562358::trans-(1S(R),2S(R))-2-Hydroxycyclohexyl nitrate::trans-(1S(R),2S(R))-2-Hydroxycyclohexylnitrate

SMILES O[C@H]1CCCC[C@@H]1O[N+]([O-])=O

InChI Key InChIKey=GVSCAKVHXWAQQJ-WDSKDSINSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293659   

TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50293659(CHEMBL562358 | trans-(1S(R),2S(R))-2-Hydroxycycloh...)
Affinity DataKi:  4.37E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50293659(CHEMBL562358 | trans-(1S(R),2S(R))-2-Hydroxycycloh...)
Affinity DataKi:  9.86E+5nMAssay Description:Noncompetitive inhibition of human carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50293659(CHEMBL562358 | trans-(1S(R),2S(R))-2-Hydroxycycloh...)
Affinity DataKi:  2.21E+8nMAssay Description:Noncompetitive inhibition of human carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Atat£Rk University

Curated by ChEMBL
LigandPNGBDBM50293659(CHEMBL562358 | trans-(1S(R),2S(R))-2-Hydroxycycloh...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed