BDBM50294169 5-chloro-1H-indole::CHEMBL555013

SMILES Clc1ccc2[nH]ccc2c1

InChI Key InChIKey=MYTGFBZJLDLWQG-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294169   

TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50294169(5-chloro-1H-indole | CHEMBL555013)
Affinity DataKi:  4.30E+6nMAssay Description:Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 4 group A member 2(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50294169(5-chloro-1H-indole | CHEMBL555013)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity towards Nurr1 ligand binding domain (unknown origin) measured by microscale thermophoresis (MST) methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294169(5-chloro-1H-indole | CHEMBL555013)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294169(5-chloro-1H-indole | CHEMBL555013)
Affinity DataIC50:  1.51E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair