BDBM50294495 (2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)ethylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)butanoic acid)::2-Amino-4-{(2S,3S,4R,5R)-5-[6-(2-biphenyl-4-yl-ethylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-ylmethylsulfanyl}-butyric acid::CHEMBL555352

SMILES NC(CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCc3ccc(cc3)-c3ccccc3)ncnc12)C(O)=O

InChI Key InChIKey=WZMUJUUYKWVGEE-FOYDDCNASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294495   

TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DNMT3b2 at 45 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed