BDBM50294555 (2R,3R,4S,5S)-2-(6-(2-(biphenyl-4-yl)ethylamino)-9H-purin-9-yl)-5-(((S)-pyrrolidin-3-ylthio)methyl)tetrahydrofuran-3,4-diol::CHEMBL551174

SMILES O[C@@H]1[C@@H](CS[C@H]2CCNC2)O[C@H]([C@@H]1O)n1cnc2c(NCCc3ccc(cc3)-c3ccccc3)ncnc12

InChI Key InChIKey=GUQWGWJSVHHGHZ-AKIIDSJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294555   

TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294555((2R,3R,4S,5S)-2-(6-(2-(biphenyl-4-yl)ethylamino)-9...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294555((2R,3R,4S,5S)-2-(6-(2-(biphenyl-4-yl)ethylamino)-9...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed