BDBM50294708 4-((2-chlorobenzyl)(1-(1-isopropyl-1H-tetrazol-5-yl)ethyl)amino)-2-chlorobenzonitrile::CHEMBL564015

SMILES CC(C)n1nnnc1C(C)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=ZYOLWNDWLWOCNQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294708   

TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294708(4-((2-chlorobenzyl)(1-(1-isopropyl-1H-tetrazol-5-y...)
Affinity DataIC50:  32nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294708(4-((2-chlorobenzyl)(1-(1-isopropyl-1H-tetrazol-5-y...)
Affinity DataIC50:  80nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294708(4-((2-chlorobenzyl)(1-(1-isopropyl-1H-tetrazol-5-y...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed