BDBM50295336 CHEMBL4163172

SMILES CNC(=O)c1cnc(NC2CCN(CC2)c2ccccn2)c(NCc2ccc(F)c(Oc3ccccc3)c2)c1

InChI Key InChIKey=DAYAIOIYCDOBQR-UHFFFAOYSA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295336   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50295336(CHEMBL4163172)
Affinity DataKd:  250nMAssay Description:Binding affinity to Mycobacterium tuberculosis InhA in presence of NADH by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50295336(CHEMBL4163172)
Affinity DataIC50:  297nMAssay Description:Inhibition of Mycobacterium tuberculosis InhA using 2-trans-dodecenoyl-CoA as substrate in presence of NADH after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50295336(CHEMBL4163172)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to Mycobacterium tuberculosis InhA in presence of NAD+ by surface plasmon resonance assayMore data for this Ligand-Target Pair