BDBM50296316 (3R)-1-Azabicyclo[2.2.2]oct-3-yl9-hydroxy-9H-fluorene-9-carboxylate::CHEMBL563887

SMILES OC1(C(=O)O[C@H]2CN3CCC2CC3)c2ccccc2-c2ccccc12

InChI Key InChIKey=VJOYACFUOINUHV-IBGZPJMESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296316   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50296316((3R)-1-Azabicyclo[2.2.2]oct-3-yl9-hydroxy-9H-fluor...)
Affinity DataIC50:  1.14nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50296316((3R)-1-Azabicyclo[2.2.2]oct-3-yl9-hydroxy-9H-fluor...)
Affinity DataIC50:  0.260nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50296316((3R)-1-Azabicyclo[2.2.2]oct-3-yl9-hydroxy-9H-fluor...)
Affinity DataIC50:  0.920nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed