BDBM50297304 CHEMBL560741::{2-[3-(4-Fluoro-benzyl)-1H-inden-2-yl]-ethyl}-dimethyl-amine

SMILES CN(C)CCC1=C(Cc2ccc(F)cc2)c2ccccc2C1

InChI Key InChIKey=FRXWLMMHSBOBJK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297304   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50297304(CHEMBL560741 | {2-[3-(4-Fluoro-benzyl)-1H-inden-2-...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50297304(CHEMBL560741 | {2-[3-(4-Fluoro-benzyl)-1H-inden-2-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50297304(CHEMBL560741 | {2-[3-(4-Fluoro-benzyl)-1H-inden-2-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant CYP2D6 in presence of NADPH generating systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed