BDBM50299777 CHEMBL573761::N-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide::Oxo-3-phenylimidazolidine-1-carboxamide, 2
SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC
InChI Key InChIKey=MCTIWUDXKBCHRY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50299777
Affinity DataKi: 1.70nMAssay Description:Inhibition of recombinant c-met-mediated gastrin phosphorylation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition assay using kinase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of GST-tagged c-Met expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of HGF-mediated c-met autophosphorylation in serum-starved human PC3 cells after 1 hr by electrochemiluminescent immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of c-Met in human DU145 cells assessed as cell scatteringMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of TPR-Met assessed as autophosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition assay using kinase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of c-Met in human A549 cells by wound healing assayMore data for this Ligand-Target Pair