BDBM50299804 4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine::CHEMBL574231

SMILES Fc1ccc(Oc2cccc(F)c2C2CCNCC2)cc1

InChI Key InChIKey=WPYMMOOTBZOFOZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299804   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299804(4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine |...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299804(4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine |...)
Affinity DataKi:  97nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299804(4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine |...)
Affinity DataKi:  156nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299804(4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine |...)
Affinity DataKi:  157nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed