BDBM50300465 (+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid::5-(biphenyl-4-yl)-3-hydroxypentanoic acid::CHEMBL572982

SMILES OC(CCc1ccc(cc1)-c1ccccc1)CC(O)=O

InChI Key InChIKey=ILGSIIFHQGOKKV-UHFFFAOYSA-N

Data  17 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50300465   

TargetInterstitial collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  3.66E+4nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human recombinant ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human recombinant ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465((+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid | 5...)
Affinity DataIC50: >9.80E+4nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed