BDBM50301929 4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-2-(3-methoxyphenyl)cyclohexyl)methyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL571799

SMILES CO[C@H]1CN(C[C@@H]2CCCC[C@@]2(O)c2cccc(OC)c2)CC[C@H]1NC(=O)c1cc(Cl)c(N)cc1OC

InChI Key InChIKey=POJMJIIKSJRQPV-QZOFJNMOSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50301929   

TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50:  159nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed