BDBM50302107 CHEMBL567893::Grassystatin A
SMILES COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](OC(=O)[C@@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C)[C@@H](C)O
InChI Key InChIKey=JZYWSTGTBRHGTL-BIXXXADNSA-N
Data 75 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 75 hits for monomerid = 50302107
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cathepsin D in human MCF7 cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin E after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin D after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataIC50: 4.61E+4nMAssay Description:Inhibition of ADAM9More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
Affinity DataIC50: 0.886nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin X after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cathepsin E in human MCF7 cells by fluorescence assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TACE after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tryptase beta2 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ADAM9 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of calpain 1 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 1 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 2 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 3 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 4 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 5 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 6 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 7 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 8 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 9 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 10 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse caspase 11 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of caspase 14 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin B after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin C after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin H after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin K after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin S after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin V after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin Z after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of chymase after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP4 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP8 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP9 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1(Sus scrofa (Pig))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of porcine pancreatic elastase after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of factor 10a after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of factor 11a after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of kallikrein 4 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of kallikrein 5 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of kallikrein 8 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP1 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
University Of Florida
Curated by ChEMBL
University Of Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ADAM10 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP2 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP3 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP7 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP8 catalytic domain after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair