BDBM50303328 (2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)carbonyl]amino}ethyl)Phosphinyl]-(2S)-2-[(3-phenylisoxazol-5-yl)methyl]-1-oxopropyl}amino)-3-phenyl Propanoic Acid::CHEMBL567628

SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1cc(no1)-c1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=YJNWDJIIFRGLRO-FFYHKYONSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50303328   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303328((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)c...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human somatic ACE in presence of bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303328((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)c...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303328((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)c...)
Affinity DataKi:  7.70nMAssay Description:Inhibition of human somatic ECE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303328((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)c...)
Affinity DataKi:  32nMAssay Description:Inhibition of human somatic ACE in presence of 1:100 diluted SHR rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303328((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)c...)
Affinity DataKi:  110nMAssay Description:Inhibition of human somatic ACE in presence of 1:100 diluted SHR rat plasma complemented with 5 uM serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303328((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)c...)
Affinity DataKi:  340nMAssay Description:Inhibition of human somatic ACE in presence of 1:50 diluted SHR rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303328((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)c...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human somatic NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303328((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1{[(benzyloxy)c...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed