BDBM50303648 (2R)-2-[(4-benzylphenoxy)methyl]pyrrolidine::(R)-2-(4-Benzylphenoxymethyl)pyrrolidine::CHEMBL571091

SMILES C(Oc1ccc(Cc2ccccc2)cc1)[C@H]1CCCN1

InChI Key InChIKey=NXNMORHGFGYRDN-QGZVFWFLSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303648   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303648((2R)-2-[(4-benzylphenoxy)methyl]pyrrolidine | (R)-...)
Affinity DataIC50:  449nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303648((2R)-2-[(4-benzylphenoxy)methyl]pyrrolidine | (R)-...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair