BDBM50304149 1H-indazol-6-amine::CHEMBL594707::cid_81423

SMILES Nc1ccc2cn[nH]c2c1

InChI Key InChIKey=KEJFADGISRFLFO-UHFFFAOYSA-N

Data  2 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304149   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50304149(1H-indazol-6-amine | CHEMBL594707 | cid_81423)
Affinity DataIC50: >1.99E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Uned

Curated by ChEMBL
LigandPNGBDBM50304149(1H-indazol-6-amine | CHEMBL594707 | cid_81423)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant NOS1 assessed as citrulline formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50304149(1H-indazol-6-amine | CHEMBL594707 | cid_81423)
Affinity DataEC50:  9.02E+3nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50304149(1H-indazol-6-amine | CHEMBL594707 | cid_81423)
Affinity DataEC50:  2.16E+4nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay