BDBM50305842 CHEMBL603656::trans-4-((5-(2-(4-fluorobenzylcarbamoyl)-6-methylpyridin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylic acid
SMILES Cc1cc(cc(n1)C(=O)NCc1ccc(F)cc1)-c1nnn(C[C@H]2CC[C@@H](CC2)C(O)=O)n1
InChI Key InChIKey=KOTGODCEORJYIF-QAQDUYKDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50305842
Affinity DataKi: 4.40nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP25More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of ADAMTS4More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP24More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP26More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human OAT3 expressed in HEK cells assessed as reduction of [3H]-estrone sulfate uptake by radioactivity counting analysisMore data for this Ligand-Target Pair