BDBM50307481 (S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-3-phenylpropanamide::CHEMBL578478
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1
InChI Key InChIKey=XGLBOPYPKBXJKE-KGSCVCOFSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50307481
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of 26S proteasome beta 1 using nLPnLD as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based competitive a...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of 26S proteasome beta 5 using LLVY as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based compet...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based competitive a...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of catalytic activity of immunoproteasome 20s subunit beta2 in human Raji cells incubated for 1 hr by BODIPY(FL)-LU-112 probe based compet...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of catalytic activity of constitutive proteasome 20s subunit beta1 in human Raji cells incubated for 1 hr by Cy5-NC-001 probe based compet...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry
Curated by ChEMBL
Leiden Institute Of Chemistry
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 26S proteasome beta 2 using RLR as substrateMore data for this Ligand-Target Pair