BDBM50308499 CHEMBL602722::Ethyl 5-(4-chlorobenzoyl)-4-phenylthiazol-2-ylcarbamate::cid_7315332

SMILES CCOC(=O)Nc1nc(c(s1)C(=O)c1ccc(Cl)cc1)-c1ccccc1

InChI Key InChIKey=QLDONWGCRXGAIQ-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50308499   

TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50308499(CHEMBL602722 | Ethyl 5-(4-chlorobenzoyl)-4-phenylt...)
Affinity DataKi:  487nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50308499(CHEMBL602722 | Ethyl 5-(4-chlorobenzoyl)-4-phenylt...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50308499(CHEMBL602722 | Ethyl 5-(4-chlorobenzoyl)-4-phenylt...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50308499(CHEMBL602722 | Ethyl 5-(4-chlorobenzoyl)-4-phenylt...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-603 from human adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50308499(CHEMBL602722 | Ethyl 5-(4-chlorobenzoyl)-4-phenylt...)
Affinity DataIC50: >5.52E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50308499(CHEMBL602722 | Ethyl 5-(4-chlorobenzoyl)-4-phenylt...)
Affinity DataEC50: >1.67E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay