BDBM50310474 4-(1-cyclobutyl-5-methyl-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-amine::CHEMBL1079135
SMILES Cc1ccc2n(C3CCC3)c(nc2c1)-c1nonc1N
InChI Key InChIKey=WJBVKTYQLWGNGE-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50310474
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair