BDBM50310475 (2-(4-amino-1,2,5-oxadiazol-3-yl)-1-cyclobutyl-1H-benzo[d]imidazol-5-yl)methanol::CHEMBL1080970
SMILES Nc1nonc1-c1nc2cc(CO)ccc2n1C1CCC1
InChI Key InChIKey=WMPGRCGEFQMAES-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50310475
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair