BDBM50310690 CHEMBL1078411::Cis-(S)-2-amino-N-((1R,2R)-1-cyano-2-phenylcyclopropyl)-3-(thiophen-2-yl)propanamide

SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N

InChI Key InChIKey=FUYOZZGSCQXNCB-VYDXJSESSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50310690   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloblastin(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Proteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-cathepsin H(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cathepsin HMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed