BDBM50312990 (R,S)-3-(3-(2,3-dihydroxypropylamino)phenyl)-4-(5-fluoro-1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione::CHEMBL1082152
SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cccc(NCC(O)CO)c2)c2cc(F)ccc12
InChI Key InChIKey=RPGZQOOZHIEPJW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 34 hits for monomerid = 50312990
Affinity DataKd: 0.0530nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 0.0530nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 4.00E+4nMAssay Description:Inhibition of AURKBMore data for this Ligand-Target Pair
Affinity DataKd: 4.00E+4nMAssay Description:Inhibition of CDK11More data for this Ligand-Target Pair
Affinity DataKd: 4.00E+4nMAssay Description:Inhibition of AURKAMore data for this Ligand-Target Pair
Affinity DataKd: 2.30E+4nMAssay Description:Inhibition of AURKCMore data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Roche Palo Alto
Curated by ChEMBL
Roche Palo Alto
Curated by ChEMBL
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Roche Palo Alto
Curated by ChEMBL
Roche Palo Alto
Curated by ChEMBL
Affinity DataKd: 1.5nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair