BDBM50315599 5-Dimethylamino-2-(2-furyl)-7-[4-(methoxyphenyl)-acetyl]amino-[1,2,4]triazolo[1,5-a]-[1,3,5]triazine::CHEMBL1089463

SMILES COc1ccc(CC(=O)Nc2nc(nc3nc(nn23)-c2ccco2)N(C)C)cc1

InChI Key InChIKey=JLFPCGNSVPGCPV-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315599   

TargetAdenosine receptor A3(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50315599(5-Dimethylamino-2-(2-furyl)-7-[4-(methoxyphenyl)-a...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [125I]-I-AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50315599(5-Dimethylamino-2-(2-furyl)-7-[4-(methoxyphenyl)-a...)
Affinity DataKi:  8.74E+3nMAssay Description:Displacement of [3H]R-PIA from adenosine A1 receptor in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50315599(5-Dimethylamino-2-(2-furyl)-7-[4-(methoxyphenyl)-a...)
Affinity DataKi:  1.03E+4nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50315599(5-Dimethylamino-2-(2-furyl)-7-[4-(methoxyphenyl)-a...)
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed