BDBM50316575 CHEMBL1095229::Ethyl2-(6-chloro-2,4,dioxo-1,2,3,4-tetrahydropyrimidin-5-ylamino)-2-oxoethanoate

SMILES CCOC(=O)C(=O)Nc1c(Cl)[nH]c(=O)[nH]c1=O

InChI Key InChIKey=GCCNRPWCWIPKRX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316575   

Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50316575(CHEMBL1095229 | Ethyl2-(6-chloro-2,4,dioxo-1,2,3,4...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50316575(CHEMBL1095229 | Ethyl2-(6-chloro-2,4,dioxo-1,2,3,4...)
Affinity DataKi:  8.32E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-inhibitor complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50316575(CHEMBL1095229 | Ethyl2-(6-chloro-2,4,dioxo-1,2,3,4...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed