BDBM50317179 2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]-beta-carboline-2-ium diiodide::CHEMBL1087458

SMILES C[n+]1ccc2c(c1)n(CCCCCCCCCn1c3ccccc3c3cc[n+](C)cc13)c1ccccc21

InChI Key InChIKey=XBLBEGLFURYCBO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50317179   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of BChE in equine serum using butyrylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  0.492nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  0.507nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317179(2-Methyl-9-[9-(2-methyl-beta-carboline-9-yl)nonyl]...)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed