BDBM50317603 8-(cyclopentyloxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one::8-(cyclopentyloxy)-4-[(3,5-dichloropyridin-4-yl)amino]-7-methoxy-2H-chromen-2-one::CHEMBL1096812

SMILES COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OC1CCCC1

InChI Key InChIKey=YUTTWVBLGONANE-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317603   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50317603(8-(cyclopentyloxy)-4-(3,5-dichloropyridin-4-ylamin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of NH2-terminal His6-tagged PDE4B catalytic domain (unknown origin) using Cyclic AMP as substrate incubated for 10 mins followed by substr...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50317603(8-(cyclopentyloxy)-4-(3,5-dichloropyridin-4-ylamin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair