BDBM50317624 4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-yloxy)hexyl)phenoxy)butanoic acid::CHEMBL1099330

SMILES OC(=O)CCCOc1cccc(CCCCCCOc2cc(cc(n2)-c2ccccc2)-c2ccccc2)c1CCC(O)=O

InChI Key InChIKey=IQMZIBZJCFEUSM-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50317624   

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50:  205nMAssay Description:Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50:  3.06E+3nMAssay Description:Antagonist activity at FLAG-tagged human BLT2 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of CYP2C9 fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as reduction of current amplitudeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50:  0.480nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50: >7.50E+3nMAssay Description:Inhibition of CYP2D6 flourescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50: >7.50E+3nMAssay Description:Inhibition of CYP2C19 flourescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50: >7.50E+3nMAssay Description:Inhibition of CYP3A4 fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)
Affinity DataIC50: >7.50E+3nMAssay Description:Inhibition of CYP1A2 by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed