BDBM50318491 7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclopent-3-enyl)heptanoic acid::CHEMBL1084644

SMILES CCCCC[C@H](O)C=C[C@H]1C=CC(=O)[C@@H]1CCCCCCC(O)=O

InChI Key InChIKey=BGKHCLZFGPIKKU-OKZBNKHCSA-N

Data  1 KI  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50318491   

TargetSolute carrier organic anion transporter family member 2A1(Rattus norvegicus (Rat))
Albert Einstein College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataKi:  286nMAssay Description:TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor subfamily 4 group A member 2(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor subfamily 4 group A member 2(Rattus norvegicus)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in rat N27-A cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor subfamily 4 group A member 2(Mus musculus)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in mouse MN9D cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor subfamily 4 group A member 2(Mus musculus)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in mouse MN9D cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor subfamily 4 group A member 2(Rattus norvegicus)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in rat N27-A cells measured by NBRE-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  1.51E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 4 group A member 2(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50318491(7-((1R,2S)-2-((S)-3-hydroxyoct-1-enyl)-5-oxocyclop...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at Nurr1 in human SK-N-BE(2)-C cells measured by Gal4-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed