BDBM50318653 3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxamide::3-amino-N-(3-fluorophenyl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide::CHEMBL1084955::NadD inhibitor 3_02::US8785499, 3_02
SMILES Nc1c(sc2nc(ccc12)-c1cccs1)C(=O)Nc1cccc(F)c1
InChI Key InChIKey=UCTSEHMMSSIODN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50318653
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of NaMN substrate by malachite gre...More data for this Ligand-Target Pair
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataKi: 1.80E+4nM IC50: 3.60E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli)
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataKi: 2.10E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli)
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataKi: 2.50E+4nM IC50: 6.50E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataKi: 3.20E+4nMAssay Description:Inhibition of Bacillus anthracis nicotinate-nucleotide adenylyltransferase preincubated for 5 mins before addition of ATP substrate by malachite gree...More data for this Ligand-Target Pair
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataKi: 3.20E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli)
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 6.50E+4nMpH: 7.5 T: 2°CAssay Description:A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,...More data for this Ligand-Target Pair