BDBM50319967 6-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)pyridin-3-yl)-1H-indole::CHEMBL1085779

SMILES CN1C[C@@H]2C[C@H]1CN2c1ccc(cn1)-c1ccc2cc[nH]c2c1

InChI Key InChIKey=JHVKOOCZASOHSP-IRXDYDNUSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50319967   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319967(6-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319967(6-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319967(6-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human alpha7 nACHR expressed in Xenopus oocyte assessed as activation of current by voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed