BDBM50320792 CHEMBL1165388::Ethyl4-(5-[(2,4-diamino-6-quinazolinyl)methyl]amino-2-methoxyphenoxy)butanoate::ethyl 4-(5-{[(2,4-diaminoquinazolin-6-yl)methyl]amino}-2-methoxyphenoxy)butanoate
SMILES CCOC(=O)CCCOc1cc(NCc2ccc3nc(N)nc(N)c3c2)ccc1OC
InChI Key InChIKey=YUHXPHNBJFUHSN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50320792
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 5.68nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 9.60nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68.3nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataIC50: 23.8nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair