BDBM50321522 CHEMBL1171164::N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-1-(3-(trifluoromethyl)benzyl)-1H-pyrazole-4-carboxamide

SMILES CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3cnn(Cc4cccc(c4)C(F)(F)F)c3)sc12

InChI Key InChIKey=CEABWOSUDRMZCJ-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50321522   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321522(CHEMBL1171164 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321522(CHEMBL1171164 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321522(CHEMBL1171164 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321522(CHEMBL1171164 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321522(CHEMBL1171164 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321522(CHEMBL1171164 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321522(CHEMBL1171164 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human adenosine A2B receptor expressed in CHO cells assessed as decrease in cellular cAMP level after 20 to 25 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321522(CHEMBL1171164 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of adenosine-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed