BDBM50322938 2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL1210565

SMILES Fc1cc(F)cc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2ccc(F)c(Cl)c2)c2ccccn2)c1

InChI Key InChIKey=IWYVKGJZWVPVBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322938   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322938(2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322938(2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322938(2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed