BDBM50330426 5-Fluoro-4-hydroxybiphenyl-3-carboxylic acid::CHEMBL1275725

SMILES OC(=O)c1cc(cc(F)c1O)-c1ccccc1

InChI Key InChIKey=TWDUDGDZLVAYPU-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330426   

TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330426(5-Fluoro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human wild type AKR1C1 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330426(5-Fluoro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330426(5-Fluoro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human AKR1C1-mediated progesterone metabolism expressed in bovine aortic endothelial cells assessed as formation of 20alpha-hydroxyprog...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed