BDBM50330789 CHEMBL1277501::N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-propane-1,3-diamine

SMILES CNCCCN(c1ccccc1)c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=XNCBCWQLSZMOOC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50330789   

TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed