BDBM50331612 CHEMBL1290072::N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine

SMILES COc1ccc(CNc2ccnc3oc4ccccc4c23)cc1

InChI Key InChIKey=MNMQBQOLMHVBJT-UHFFFAOYSA-N

Data  22 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 50331612   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi:  150nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi:  400nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human ABL2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human PDGFR-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human IRAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human DYRK1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomeodomain-interacting protein kinase 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human HIPK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human INK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human Nek3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human WEE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human CK1-alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human p38-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C iota type(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human PKC-iotaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human ERK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human PKC-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human Aurora CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  3.92E+5nMAssay Description:Inhibition of human ABL1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  1.94E+5nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  1.29E+5nMAssay Description:Inhibition of human CDK6/Cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase VRK1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  1.29E+5nMAssay Description:Inhibition of human VRK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  6.22E+5nMAssay Description:Inhibition of human InsRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  2.71E+5nMAssay Description:Inhibition of human PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  3.76E+5nMAssay Description:Inhibition of human CDK4/Cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor-related protein(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibition of human InsRRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(CHEMBL1290072 | N-(4-methoxybenzyl)benzofuro[2,3-b...)
Affinity DataIC50:  7.59E+5nMAssay Description:Inhibition of human LIMK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed