BDBM50331834 5-butyramido-2-sulfamoyl-1,3,4-thiadiazole::CHEMBL1288787

SMILES CCCC(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=HZIYHIRJHYIRQO-UHFFFAOYSA-N

Data  4 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50331834   

TargetCarbonic anhydrase 4(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50331834(5-butyramido-2-sulfamoyl-1,3,4-thiadiazole | CHEMB...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of recombinant human CA4 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50331834(5-butyramido-2-sulfamoyl-1,3,4-thiadiazole | CHEMB...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of recombinant human CA2 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50331834(5-butyramido-2-sulfamoyl-1,3,4-thiadiazole | CHEMB...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of recombinant human CA9 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50331834(5-butyramido-2-sulfamoyl-1,3,4-thiadiazole | CHEMB...)
Affinity DataKi:  54nMAssay Description:Inhibition of recombinant human CA1 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndochitinase A1(Neosartorya fumigata (Aspergillus fumigatus))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50331834(5-butyramido-2-sulfamoyl-1,3,4-thiadiazole | CHEMB...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Aspergillus fumigatus ChiA1 expressed in Pichia pastoris after 70 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed