BDBM50332553 CHEMBL1630707::N-(3-(4-(5-(cyclopentyloxy)pyridin-2-yloxy)phenyl)propyl)acetamide::US8470841, 7

SMILES CC(=O)NCCCc1ccc(Oc2ccc(OC3CCCC3)cn2)cc1

InChI Key InChIKey=ZLKMOUBQZRCJNB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50332553   

TargetAcetyl-CoA carboxylase 2 [151-2458](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50332553(CHEMBL1630707 | N-(3-(4-(5-(cyclopentyloxy)pyridin...)
Affinity DataIC50:  1.28E+3nMpH: 7.5 T: 2°CAssay Description:the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332553(CHEMBL1630707 | N-(3-(4-(5-(cyclopentyloxy)pyridin...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332553(CHEMBL1630707 | N-(3-(4-(5-(cyclopentyloxy)pyridin...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50332553(CHEMBL1630707 | N-(3-(4-(5-(cyclopentyloxy)pyridin...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed