BDBM50333737 3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl)-N,N,5,7-tetramethylbenzo[b]thiophene-2-carboxamide::CHEMBL1644016

SMILES COc1ccccc1CC(=O)NCCc1ccc(cc1)-c1c(sc2c(C)cc(C)cc12)C(=O)N(C)C

InChI Key InChIKey=RFLCCBORSMQZKZ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333737   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333737(3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333737(3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333737(3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl...)
Affinity DataKi:  17nMAssay Description:Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333737(3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl...)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at human EP4 receptor in HEK293 cells by cell-based functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed