BDBM50334670 2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline::CHEMBL1642568
SMILES Cc1cc2c3cc(C)ccc3nc(CCc3nc(cn3C)-c3ccccc3)n2n1
InChI Key InChIKey=PXIUKGSKVQLIBW-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50334670
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5AMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4D6More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE1BMore data for this Ligand-Target Pair