BDBM50335280 CHEMBL1651354::N-(Benzylcarbamoyl)-leucyl-methylazaalanine-nitrile::acs.jmedchem.1c00409_ST.408

SMILES CC(C)C[C@H](NC(=O)NCc1ccccc1)C(=O)N(C)N(C)C#N

InChI Key InChIKey=JESRGSWARNNMLP-HNNXBMFYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50335280   

TargetCathepsin K(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335280(CHEMBL1651354 | N-(Benzylcarbamoyl)-leucyl-methyla...)
Affinity DataKi:  0.0110nMAssay Description:Inhibition of human recombinant cathepsin K after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335280(CHEMBL1651354 | N-(Benzylcarbamoyl)-leucyl-methyla...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335280(CHEMBL1651354 | N-(Benzylcarbamoyl)-leucyl-methyla...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50335280(CHEMBL1651354 | N-(Benzylcarbamoyl)-leucyl-methyla...)
Affinity DataKi:  0.650nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50335280(CHEMBL1651354 | N-(Benzylcarbamoyl)-leucyl-methyla...)
Affinity DataIC50:  7.59E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed