BDBM50336396 CHEMBL1668262::trans-4-((2S)-2-(2-(4-chloro-2-methoxypyridin-3-yl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)cyclohexanecarboxylic acid

SMILES COc1ccc(-c2nc3cc(F)c(F)cc3n2[C@@H](C2CCCCC2)C(=O)N[C@H]2CC[C@@H](CC2)C(O)=O)c(Cl)n1

InChI Key InChIKey=MHXBXKCNLBAHRJ-UAVUOLJFSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336396   

TargetBile acid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336396(CHEMBL1668262 | trans-4-((2S)-2-(2-(4-chloro-2-met...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at Gal4-fused human FXR by luciferase reporter gene transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336396(CHEMBL1668262 | trans-4-((2S)-2-(2-(4-chloro-2-met...)
Affinity DataIC50:  290nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed