BDBM50336546 CHEMBL1673415::Palmostatin B

SMILES CCCCCCCCCC[C@H]1[C@H](CCc2ccc(OC)c(OC)c2)OC1=O

InChI Key InChIKey=ASVWFAVGLYUDFD-PMACEKPBSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50336546   

TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataKi:  34nMAssay Description:Inhibition of APT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of APT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylserine lipase ABHD16A(Homo sapiens (Human))
University Of Helsinki

Curated by ChEMBL
LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataIC50:  57nMAssay Description:Reversible inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 40 fold compound dilution and subsequent 1-LG s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylserine lipase ABHD16A(Homo sapiens (Human))
University Of Helsinki

Curated by ChEMBL
LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataIC50:  99nMAssay Description:Inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylserine lipase ABHD16A(Homo sapiens (Human))
University Of Helsinki

Curated by ChEMBL
LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataIC50:  100nMAssay Description:Inhibition of ABHD16A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataIC50:  670nMAssay Description:Inhibition of APT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50336546(CHEMBL1673415 | Palmostatin B)
Affinity DataIC50:  38nMAssay Description:Inhibition of APT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed