BDBM50339286 5-(Difluoromethyl)-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one::CHEMBL1689659

SMILES FC(F)c1cc(=O)n2[nH]c(c(-c3ccccc3)c2n1)C(F)(F)F

InChI Key InChIKey=JQAGJROIHSNEGB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339286   

TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50339286(5-(Difluoromethyl)-3-phenyl-2-(trifluoromethyl)pyr...)
Affinity DataEC50:  4.29E+3nMAssay Description:Activation of KCNQ2/Q3 expressed in CHO cells by atomic absorption Rb'+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed