BDBM50340796 CHEMBL1760687::N-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,2,4-triazol-3-yl)phenyl)isoxazole-5-carboxamide
SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(NC(=O)c2ccno2)cc1
InChI Key InChIKey=GYGISWPQEUFTKD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50340796
Affinity DataIC50: 8nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at PXRMore data for this Ligand-Target Pair